Highly regioselective gold-catalyzed formal hydration of propargylic gem-difluorides
2017
Herein, we report a highly regioselective gold-catalyzed formal hydration of propargylic gem-difluorides. Not only does this transformation provide access to versatile fluorinated building blocks that were difficult or hardly possible to access beforehand, but it also represents a rare case of a highly regioselective gold-catalyzed hydroalkoxylation of internal alkynes and puts forward the utility of the difluoromethylene unit as a directing group in catalysis.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
86
References
18
Citations
NaN
KQI