Modern strategies in AML treatment

Acute myeloid leukemia (AML) is a complex disease that is characterized by diverse genetic and epigenetic abnormalities. The heterogeneity of AML subtypes implies that improvements in clinical outcome will require the development of therapies that are specific for each subtype of the disease and the design of novel clinical trials to test these strategies. In this review, we briefly summarize recent clinical trials, the genetic diversity of AML, and the use of minimal residual disease in the treatment of AML.