966 DETECTION OF PROSTATE CANCER BY URINE PROTEOMICS

these responses is high, typically only 5-20% of patients demonstrate a response to any given antigen, which has limited the usefulness of single antigen responses as biomarkers. The recent development of protein microarrays may offer an ideal tool for screening for immune response to tumor antigens. These arrays offer the advantage that hundreds to thousands of different proteins can be printed and screened simultaneously and only require a few microliters of serum per assay.