Synchrotron Radiation X-Ray Phase Micro-computed Tomography as a New Method to Detect Iron Oxide Nanoparticles in the Brain

Marilena Marinescu,Max Langer,Alexane Durand,Cécile Olivier,Alexandre Chabrol,Hugo Rositi,Fabien Chauveau,T.-H. Cho,Norbert Nighoghossian,Yves Berthezène,Françoise Peyrin,Marlène Wiart

Synchrotron Radiation X-Ray Phase Micro-computed Tomography as a New Method to Detect Iron Oxide Nanoparticles in the Brain

2013

Marilena Marinescu
Max Langer
Alexane Durand
Cécile Olivier
Alexandre Chabrol
Hugo Rositi
Fabien Chauveau
T.-H. Cho
Norbert Nighoghossian
Yves Berthezène
Françoise Peyrin
Marlène Wiart

Purpose The purpose of this study was to introduce synchrotron radiation X-ray phase computed tomography (SR-PCT) as a new method of visualizing ultrasmall superparamagnetic particles of iron oxide (USPIO) distribution into the brains of mice with neuroinflammation.

Keywords:

Nuclear medicine
Medicine
Radiology
Computed tomography
Synchrotron radiation
Iron oxide nanoparticles
Phase contrast microscopy
X-ray
Iron oxide
micro computed tomography
Superparamagnetism

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