Short peptide for increasing thermal stability of transglutaminase, and application thereof

The present invention discloses a peptide for improving the thermal stability of the transglutaminase, the amino acid sequence as shown in SEQ ID NO. 1; the present invention also discloses an improved thermal stability of the transglutaminase, characterized in that short peptides containing the C-terminal amino acid as shown in SEQ ID NO.2. Application of the above-described peptide can significantly improve the thermal stability of the transglutaminase, its half-life is extended from 50 deg.] C 9.1 min to 3.7min, 1.5 fold increase; TG-tag1 melting temperature of 76.4oC, 7.5 deg.] C to improve the enzyme compared to the wild .