MBL2 and hepatitis C virus infection among injection drug users.

Elizabeth E. Brown,Mingdong Zhang,Rebecca Zarin-Pass,Toralf Bernig,Fan Chen Tseng,Nianqing Xiao,Meredith Yeager,Brian R. Edlin,Stephen J. Chanock,Thomas R. O’Brien

MBL2 and hepatitis C virus infection among injection drug users.

2008

Elizabeth E. Brown
Mingdong Zhang
Rebecca Zarin-Pass
Toralf Bernig
Fan Chen Tseng
Nianqing Xiao
Meredith Yeager
Brian R. Edlin
Stephen J. Chanock
Thomas R. O’Brien

Background Genetic variations in MBL2 that reduce circulating levels and alter functional properties of the mannose binding lectin (MBL) have been associated with many autoimmune and infectious diseases. We examined whether MBL2 variants influence the outcome of hepatitis C virus (HCV) infection.

Keywords:

Mannan-binding lectin
Infectious disease (medical specialty)
Pathology
Hepatitis C virus
Virology
Medical microbiology
Hepatitis C
Single-nucleotide polymorphism
Medicine
Genotype
Hepacivirus
Immunology
Virus
Case-control study
MBL deficiency

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