Abstract 19806: Age-Dependent Prognostic Value of Low Body Mass Index for Cardiovascular Events in Patients With ST-Segment Elevation Myocardial Infarction

Introduction: Underweight individuals have increased risk of death. The age-dependent relationship between body mass index (BMI) and subsequent cardiovascular events in patients with ST-segment Elevation Myocardial Infarction (STEMI) is not clear. Hypothesis: We tested the hypothesis that the impact of BMI on subsequent cardiovascular events following STEMI is age-dependent. Methods: Four-hundred and eighty-one subjects with STEMI were enrolled. Subjects were divided by age 65 years and BMI (20, 24, and 28). Frailty was assessed with gait speed in 200-meter walking test. Subjects were followed for cardiovascular deaths, non-fatal myocardial infarctions, non-fatal ischemic strokes, and congestive heart failure for a median of 5.5 years. Results: During the follow-up period, 103 subjects experienced cardiovascular events. In all subjects, the lowest BMI group (≤ 20) had the highest risk for cardiovascular events compared to other BMI groups (Hazard ratio [HR] in comparison to BMI 20 to 24 group was 2.19 [95...