A Convenient Method for Synthesis of 1,1-Diisopropoxycyclohexane

By one-pot method,with p-toluenesulfonic acid as catalyst,trimethyl orthoformate and cyclohexanone reacted in isopropanol to form 1,1-dimethoxycyclohexane,which,without separation,reacted furthur with isopropanol to form the title compound by distilling off the low-boiling product.Structure of the title compound was characterized by elementary analysis,~1HNMR and IR.The optimized process conditions and result were n(cyclohexanone)∶n(trimethyl orthoformate)∶n(isopropanol)∶n(p-toluenesulfonic acid)=1∶1.1∶4∶0.007,number of theoretical plates 5,reaction time 15 h,yield 61.5% and GC content 96.4%(area normalization method).