Search for the second Peutz-Jeghers syndrome locus: exclusion of the STK13, PRKCG, KLK10, and PSCD2 genes on chromosome 19 and the STK11IP gene on chromosome 2

K. Buchet-Poyau,Hamid Mehenni,Uppala Radhakrishna,Stylianos E. Antonarakis

Search for the second Peutz-Jeghers syndrome locus: exclusion of the STK13, PRKCG, KLK10, and PSCD2 genes on chromosome 19 and the STK11IP gene on chromosome 2

2002

K. Buchet-Poyau
Hamid Mehenni
Uppala Radhakrishna
Stylianos E. Antonarakis

Pathogenic mutations in the serine/threonine kinase STK11 (alias LKB1) cause Peutz-Jeghers syndrome (PJS) in most affected individuals. However, in a considerable number of PJS-patients mutations cann

Keywords:

Genetics
Peutz–Jeghers syndrome
Locus (genetics)
STK11
Chromosome 19
Biology
KLK10
Genetic linkage
Gene mapping
Gene
Cancer research
Candidate gene
Chromosome
Molecular biology

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