Application of natural deep eutectic solvents in isolation of anthocyanins and biocatalysis with lipase

In this dissertation, 15 natural deep eutectic solvents were successfully prepared and applied for developing an eco-friendly method for extraction of anthocyanins and lipase-catalyzed (R)-1-phenylethanol synthesis. Also, the biological activity of prepared grape pomace extracts was evaluated. With natural deep eutectic solvents efficiency of the process was increased in comparison with conventional processes. Extraction and biocatalytic process were optimised using the response surface methodology afterward laboratory-developed methods were scaled up. In both processes, the recyclation of used natural deep eutectic solvents was performed, as well as isolation and purification of the final product (anthocyanins, (R)-1-phenylethanol).