A comparison of cyclic AMP signaling system in rat aortic myocytes in primary culture and aorta

Cyclic AMP (cAMP) metabolism has been studied in rat aortic myocytes grown in primary culture to characterize this second messenger system in vascular smooth muscle cells that retain responses to vasoactive drugs. It is concluded that, despite some quantitative differences, the cAMP system of rat aortic myocytes grown in primary culture has characteristics similar to those displayed in rat isolated aorta