Inhibition of muscle amino acid release by infusion of a triglyceride emulsion

Amino acid balances of 12 healthy volunteers were investigated with the forearm technique under the influence of an intravenous infusion of a long-chain triglyceride emulsion (LCT). Arterial concentrations of the amino acids declined due to a decrease of basal muscular release of most of the amino acids. Decreased phenylalanine and tyrosine output suggest that muscular proteolysis might be inhibited. With constant insulin and substantially unchanged blood glucose concentrations, this is apparently due to the increased concentration of free fatty acids.