The Human Gene Encoding Phosphatidylinositol-3 Kinase Associated p85α Is at Chromosome Region 5q12–13

The human chromosomal location of the gene encoding the phosphatidylinositol-3 kinase associated protein, p85α, has been determined by analysis of its segregation in rodent-human hybrids and by chromosome in situ hybridization using a complementary DNA clone, GRB-1. The gene for p85α is at chromosome region 5q13, perhaps near the gene encoding another receptor associated signal transducing protein, the GTPase activating protein.