Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure

Diana Cruz-Topete,Robert H. Oakley,Natalie G. Carroll,Bo He,Page Myers,Xiaojiang Xu,Megan N. Watts,Krystle Trosclair,Edward Glasscock,Paari Dominic,John A. Cidlowski

Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure

2019

Diana Cruz-Topete
Robert H. Oakley
Natalie G. Carroll
Bo He
Page Myers
Xiaojiang Xu
Megan N. Watts
Krystle Trosclair
Edward Glasscock
Paari Dominic
John A. Cidlowski

Background The contribution of glucocorticoids to sexual dimorphism in the heart is essentially unknown. Therefore, we sought to determine the sexually dimorphic actions of glucocorticoid signaling...

Keywords:

Glucocorticoid
Endocrinology
Cardiology
Diabetes mellitus
Internal medicine
Glucocorticoid receptor
Gene expression
Medicine
Heart failure
Sexual dimorphism

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