Global gene expression analysis in liver of obese diabetic db/db mice treated with metformin
2006
Aims/hypothesis
Metformin is widely used as a hypoglycaemic reagent for type 2 diabetes. While the reduction of hepatic gluconeogenesis is thought to be a key effect, the detailed molecular mechanism of action of metformin remains to be elucidated. To gain insight into this, we performed a global gene expression profiling study.
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