POOR OUTCOMES ASSOCIATED WITH DIGOXIN DISCONTINUATION IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF) MAY DIFFER BY BETA-BLOCKER USE

Poor outcomes associated with digoxin discontinuation have been shown to be significantly worse in the subgroup of patients with HFrEF not receiving (vs receiving) beta-blockers (p for interaction, 0.044; PMID: 31370952). We examined this association separately in patients with HFrEF receiving and