Effect of Pu-erh Tea on Blood Lipid and Plasma TXB_2 and 6-Keto-PGF_(1α) Levels in Hyperlipidemic Mice

2011 
In order to establish a hyperlipidemic mouse model by feeding high-fat diet,SD mice fed Pu-erh tea at the dosages of 0.5,1.0 g/(kg·d) and 2.0 g/(kg·d) for 35 consecutive days.The total cholesterol(TCHO),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C) and low-density lipoprotein cholesterol(LDL-C) in the blood of SD mice were determined.Meanwhile,plasma thromboxane-B2(TXB2) and 6-keto-prostaglandin F1α(6-keto-PGF1α) were also analyzed by ELISA.The results showed that the levels of TCHO,TC,LDL-C and TXB2 in SD mouse blood exhibited a significant reduction in treatment groups while HDL-C and 6-keto-PGF1α revealed a significant increase(P0.05;P0.01) when compared with the control group.
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