Effec tsofAdenine Arabinoside on CelularImmune Mechanisms inHumans

munesuppression ofthe humoral immunesys-tempredisposespatientstorisk fromsecondaryinfections (1, 3, 10). Gastrointestinal and cen-tral nervous system toxicity also limit theusefulness of some of the potential antiviralcompounds. Ara-C and idoxuridine have bothbeenshownto inhibitcerebellardevelopmentinfetal and young animals, causing serious con-cern