Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes

Jette Bork-Jensen,Camilla Scheele,Daniel Christophersen,Emma Nilsson,Martin Friedrichsen,Denise S. Fernandez-Twinn,Louise Groth Grunnet,Thomas Litman,Kim Holmstrøm,Birgitte F. Vind,Kurt Højlund,Henning Beck-Nielsen,Jørgen F. P. Wojtaszewski,Susan E. Ozanne,Bente Klarlund Pedersen,Pernille Poulsen,A. Vaag

Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes

2015

Jette Bork-Jensen
Camilla Scheele
Daniel Christophersen
Emma Nilsson
Martin Friedrichsen
Denise S. Fernandez-Twinn
Louise Groth Grunnet
Thomas Litman
Kim Holmstrøm
Birgitte F. Vind
Kurt Højlund
Henning Beck-Nielsen
Jørgen F. P. Wojtaszewski
Susan E. Ozanne
Bente Klarlund Pedersen
Pernille Poulsen
A. Vaag

Aims/hypothesis We aimed to identify microRNAs (miRNAs) associated with type 2 diabetes and risk of developing the disease in skeletal muscle biopsies from phenotypically well-characterised twins.

Keywords:

Insulin
Skeletal muscle
microRNA
Disease
Diabetes mellitus
Type 2 diabetes
Downregulation and upregulation
Glucose tolerance test
Endocrinology
Biology
Internal medicine

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