Klotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress

Sun Woo Lim,Long Jin,Kang Luo,Jian Jin,Yoo-Jin Shin,Sung Yi Hong,Chul-Woo Yang

Klotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress

2017

Sun Woo Lim
Long Jin
Kang Luo
Jian Jin
Yoo-Jin Shin
Sung Yi Hong
Chul-Woo Yang

Klotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress

Keywords:

FOXO3
Molecular biology
Cell biology
Manganese Superoxide Dismutase
PI3K/AKT/mTOR pathway
Tacrolimus
Oxidative stress
Biology
Diabetes mellitus
Klotho
Phosphorylation
Signal transduction
Mitochondrion
Reactive oxygen species

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