Comparison of the pharmacokinetics of intravenously administered rac-baclofen and its (−)-(R)- and (+)-(S)-enantiomers in dogs

Since only the (−) enantiomer is pharmacologically active, the pharmacokinetics of rac-baclofen and its enantiomers were studied individually in the same group of dogs to determine if there was any stereospecificity in the dry's kinetics after a single intravenous dose