Investigating the molecular basis for the virulence of Escherichia coli K5 by nuclear magnetic resonance analysis of the capsule polysaccharide.

Charles D. Blundell,Ian S. Roberts,John K. Sheehan,Andrew Almond

Investigating the molecular basis for the virulence of Escherichia coli K5 by nuclear magnetic resonance analysis of the capsule polysaccharide.

2009

Charles D. Blundell
Ian S. Roberts
John K. Sheehan
Andrew Almond

The capsular polysaccharide of Escherichia coli K5 has been hypothesised to promote virulence through its molecular mimicry of host heparan sulphate. To test this hypothesis, we hav

Keywords:

Molecular mimicry
Heparan sulphate
Immune system
Microbiology
Capsule
Polysaccharide
Escherichia coli
Virulence
Biochemistry
Biology
Host–pathogen interaction
heparan sulphate proteoglycan

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