Organocatalytic Asymmetric Vinylogous Michael Addition of Dicyanoolefins to Imine Intermediates Generated in situ from Arenesulfonylalkylindoles.

Xing‐Li Zhu,Wujun He,Liang‐Liang Yu,Chang‐Wu Cai,Zong‐Le Zuo,Da‐Bin Qin,Quan‐Zhong Liu,Linhai Jing

Organocatalytic Asymmetric Vinylogous Michael Addition of Dicyanoolefins to Imine Intermediates Generated in situ from Arenesulfonylalkylindoles.

2013

Xing‐Li Zhu
Wujun He
Liang‐Liang Yu
Chang‐Wu Cai
Zong‐Le Zuo
Da‐Bin Qin
Quan‐Zhong Liu
Linhai Jing

The present first Michael addition provides an easy and convenient approach to C-3 alkyl-substituted indole derivatives with high enantioselectivities whereas diastereoselectivity depends on the cyano substrate.

Keywords:

Imine
Indole test
Organocatalysis
Substrate (chemistry)
In situ
Chemistry
Organic chemistry
Michael reaction

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations