Research progress of application of whole blood in hemorrhagic shock resuscitation of combat casualties

Blood transfusion is an important resuscitation method for combat casualties with severe hemorrhagic shock. The optimal resuscitation plan directly influences the treatment effect of the wounded. Whole blood, once the main resuscitation fluid, was replaced by blood components for various reasons and became a supplement when there was insufficient blood components supply. With the latest evidence of whole blood application in combat casualties, the development of blood transfusion technology and the deepened clinical and basic research, we realize that the obstacles in the use of whole blood are not insurmountable and that whole blood has the advantages that blood components do not have in the treatment of combat casualties. Therefore, whole blood has once again become a research hotspot in the field of combat casualties treatment. This article reviews the development history, advantages and disadvantages of whole blood application in the resuscitation of hemorrhagic shock after combat casualties, with a view to provide reference for further clinical and basic research. Key words: Blood transfusion, whole blood; Shock, hemorrhagic; Resuscitation