Primary Amine-Functionalized Mesoporous Phenolic Resin-Supported Palladium Nanoparticles as an Effective and Stable Catalyst for Water-medium Suzuki-Miyaura Coupling Reactions.

Metal nanoparticles have been recognized and widely explored as unique catalysts for carbon-carbon coupling reactions. However, due to their extreme tendency to agglomeration, the generation and stabilization of metal nanoparticles in porous matrix is an important research field. Herein, a novel mesoporous phenolic resin supported palladium nanoparticles (Pd@NH2-MPRN) was prepared via direct anionic exchange followed by gentle reduction by using primary amine function-alized ordered mesoporous phenolic resin as the support. The obtained Pd@NH2-MPRN material still possessed large sur-face area and ordered two-dimensional hexagonal mesoporous structure. Meanwhile, uniform and well-dispersed palladi-um nanoparticles were formed in the mesoporous channels, which could be attributed to efficient complexation and stabili-zation effect derived from the primary amine groups. As a result, it can promote Suzuki coupling of less-activated aromatic bromides to various biaryls in water with high conversion and selecti...