Comparative strategies for correction of interferences in isotope dilution mass spectrometric determination of vanadium

Vanadium has been determined in SRM 1573a, Tomato Leaves, by isotope dilution mass spectrometry using thermal ionization (TIMS) and resonance ionization (RIMS). The capabilities of the two techniques to compensate for interferences from chromium and titanium are compared. For thermal ionization, corrections to the m/e 50 signal of 13-60% were made for interferences. The resulting V concentration had a relative standard deviation of 1.2%. Regression analysis of the data identified second-order corrections that resulted in a between-sample precision of 0.46%. Resonance ionization had a demonstrated specificity of 2000:1 against Cr and Ti interferences