Solitary neurofibroma originating from the posterior nasal septum: Transnasal endoscopic resection

Abstract Introduction The head and neck region is one of the locations of neurogenic tumors such as neurofibroma. Although mostly associated with neurofibromatosis, it can be solitary. The present study reports a very rare case of solitary neurofibroma originating from the posterior nasal septum. Case presentation A 48-year-old female presented with tumor in the right nasal cavity. The tumor, originating in the posterior nasal septum, extended to the posterior sinuses and nasopharynx. Following endoscopic and radiological assessment, the tumor was resected by transnasal endoscopic surgery. Histological examination showed the tumor to be a neurofibroma. At 14 months’ follow-up, there was no recurrence. Discussion and conclusions However rare, solitary neurofibroma must be considered in the differential diagnosis of unilateral benign tumor involving nasal and paranasal sinuses. A transnasal endoscopic approach should be considered for treatment.