Pirazolopirimidinas replaced with phenyl.
2003
Compounds of formula (I) in which R1 means C1-C6 alkyl, trifluoromethyl, hydroxy, C1-C6 alkoxy, -C (= O) OR5 or -C (= O) NR6R7, where C1-C6 alkyl is the case substituted with 1 to 3 moieties independently selected from the group consisting of hydroxy, C1-C6 alkoxy, halogen, trifluoromethyl, trifluoromethoxy, -C (= O) OR5 or -C (= O) NR6R7, and R5 represents C1-C6 alkyl, R6 and R7 independently represent each other hydrogen, C6-C10 aryl, C1-C6 alkyl, or together with the nitrogen atom to which they are attached, a 4 to 10 membered heterocyclyl, R2 means hydrogen, C1-C6 alkyl, trifluoromethyl, C1-C6 alkoxy, or R1 and R2 form, together with the carbon atom to which they are attached, C3-C8 cycloalkyl, C3-C8 cycloalkenyl or 4- to 10-membered heterocyclyl which are substituted as appropriate with up to 2 group substituents formed by C1-C6 alkyl, C1-C6 alkoxy, hydroxy, oxo, -C (= O) OR8, and R8 represents C1-C6 alkyl or benzyl, R3 means hydrogen or C1-C alkyl 6, R4 pentan-3-yl, C3-C6 cycloalkyl, X oxygen or sulfur, as well as their salts, solvates and / or solvates of the salts.
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KQI