Embedding a COVID-19 group sequential clinical trial within an ongoing trial: lessons from an unusual experience

Pierre-François Dequin,Amélie Le Gouge,Elsa Tavernier,Bruno Giraudeau,Sarah Zohar

Embedding a COVID-19 group sequential clinical trial within an ongoing trial: lessons from an unusual experience

2020

Pierre-François Dequin
Amélie Le Gouge
Elsa Tavernier
Bruno Giraudeau
Sarah Zohar

The Cape-Covid trial is an embedded clinical trial within the ongoing Cape-Cod trial. The Covid-19 pandemic appeared while we were conducting a randomized trial assessing the effectiveness of corti...

Keywords:

Statistics
severe acute respiratory syndrome coronavirus 2
Clinical trial
Pandemic
Emergency medicine
Coronavirus disease 2019
group sequential
Mathematics
Randomized controlled trial
2019 20 coronavirus outbreak

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