Composition for preventing or treating inflammatory bowel disease comprising metformin as an active ingredient
2013
The present invention relates to a composition for preventing or treating inflammatory bowel diseases comprising metformin as an active ingredient. A metformin compound or a composite of the metformin and etanercept (product name: Enbrel) have an excellent effect in maintaining the thickness of small intestines and the length of large intestines in a state similar to a normal state, an excellent effect in controlling or reducing the activity of IL-17 and TNF-a, and an excellent effect in promoting or increasing the activity of IFNr, thereby able to be practically used as a pharmaceutical composition for preventing or treating autoimmune diseases including the treatment of inflammatory bowel diseases.
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