Spectrum of breast diseases with Cyto-Histopathological correlation in a tertiary care hospital of Western Uttar Pradesh

Background: Breast lumps are a cause of concern both for the patients as well as the surgeons because of their turning into malignancy. The most valuable role of cytology in benign lesions is in the identification of proliferative lesions. Objectives: This present study was carried out to evaluate the efficacy of fine needle aspiration cytology (FNAC) in different diseases and its correlation with the histopathological findings. Material & Methods: All the lesions were categorized cytologically into 5 categories ranging from C1 to C5 as per NHS Breast Screening Programme (NHSBSP) reporting criteria. Results: This present study was carried out a total of 220 patients during a 1 year period from January 2015 to December 2015. All patients presenting with lump in the breast and all those who had FNAC of these lumps were included in this study. The age of the patients ranged from 14 to 80 years. The maximum numbers of patients were in the 20-40 year group followed by the 41-60 year group. The upper and outer quadrant was affected in 83 patients (37.7%). Benign lesions were observed in patients of all age groups, but especially the young patients were more affected. The FNAC findings were correlated with the histopathological diagnosis for evaluating the diagnostic accuracy of Cytology. The results obtained were arranged in a tabular manner and after statistical analysis were concluded. Conclusions: Diagnosis of malignancy by FNAC is a safe and definitive procedure. However, in suspicious or atypical smears it may have some limitations. For diagnosis of these lesions histopathology is considered as a ‘Gold standard’ for definitive diagnosis. FNAC is an easy, accurate and economical diagnostic procedure possible even in the OPD for palpable breast lumps. It is safe with easy repeatability yielding quick results and even obviating the need for open biopsy. Keywords: Breast, FNAC, Histopathology, Benign, Carcinoma