Assessment of Mitral Annulus Size and Function by Real-time 3-Dimensional Echocardiography in Cardiomyopathy: Comparison with Magnetic Resonance Imaging

Objective We sought to assess mitral annular (MA) size and function in hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) using real-time 3-dimensional (3D) echocardiography (RT3DE). Methods The study included 30 patients with HCM, 20 patients with DCM, and 30 control subjects. RT3DE measurements included end-systolic and end-diastolic MA area (MAA) (MAA 3D ), MA diameter 3D , MA fractional area change (MAFAC), and MA fractional shortening. In subgroup of 50 patients, magnetic resonance imaging (MRI) was used for MAA MRI and MA diameter MRI measurement. Results End-diastolic MAA 3D was larger in HCM than in control group ( P P = .001 and P = .006, respectively). End-systolic and end-diastolic MAA 3D in DCM were higher than in HCM and control groups ( P P r = 0.94, P r = 0.53, P = .02) and HCM ( r = 0.42, P Conclusion RT3DE assessment of MA size and function in control subjects and patients with cardiomyopathy is accurate and well correlated with MRI.