GW29-e0413 The effect of Shen-Yuan-Dan Capsule on autophagy gene Atg13 promoter methylation and PI3K/Akt/mTORC1 signaling pathway in atherosclerotic mice

Shen-Yuan-Dan Capsule (SYDC), a Chinese medicine used for treating angina pectoris, has anti-atherosclerotic effects in ApoE-deficient (ApoE-/-) mice. Autophagy and aberrant DNA methylation are indispensable in the pathogenesis of atherosclerosis. This study aimed to explore the methylation