Fetal Ventricular Interactions and Wall Mechanics During Ductus Arteriosus Occlusion in a Sheep Model

Abstract We investigated the effect of fetal sheep ductus arteriosus occlusion (DO) on the distribution of cardiac output and left and right ventricular function by tissue and pulsed Doppler at baseline; after 15 and 60 min of DO induced with a vascular occluder; and 15 min after release of DO. Ductal occlusion decreased fetal p O 2 . Mean left ventricular output increased ( p p