MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin
2014
Understanding how adhesion to the niche influences the behaviour of neural stem cells (NSCs) would contribute to our knowledge of tissue renewal. Farinas and colleagues have found that a metalloprotease sheds the N-cadherin ectodomain in the niche and that this participates in the activation of NSC generation and identity.
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