HOXA10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through HDAC1

Yi Zhang,Jie Chen,Shanshan Wu,Mengjiao Lv,Yong-Sheng Yu,Zhenghao Tang,Xiaohua Chen,Guoqing Zang

HOXA10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through HDAC1

2019

Yi Zhang
Jie Chen
Shanshan Wu
Mengjiao Lv
Yong-Sheng Yu
Zhenghao Tang
Xiaohua Chen
Guoqing Zang

Background Homeobox A10 (HOXA10) has been implicated in the development and progression of various human cancers. However, the precise biological functions of HOXA10 in hepatocellular carcinoma (HCC) have not been defined.

Keywords:

Apoptosis
Hepatocellular carcinoma
Cancer research
Gene knockdown
Cell cycle checkpoint
HDAC1
Chemistry
Survivin
Cyclin D1
Cell cycle
Histone deacetylase
Cell growth

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