The Role of Gastroesophageal Reflux in Relation to Symptom Onset in Patients with Proton Pump Inhibitor-Refractory Nonerosive Reflux Disease Accompanied by an Underlying Esophageal Motor Disorder

Shinya Izawa,Yasushi Funaki,Akihito Iida,Kentaro Tokudome,Yasuhiro Tamura,Naotaka Ogasawara,Makoto Sasaki,Kunio Kasugai

The Role of Gastroesophageal Reflux in Relation to Symptom Onset in Patients with Proton Pump Inhibitor-Refractory Nonerosive Reflux Disease Accompanied by an Underlying Esophageal Motor Disorder

2014

Shinya Izawa
Yasushi Funaki
Akihito Iida
Kentaro Tokudome
Yasuhiro Tamura
Naotaka Ogasawara
Makoto Sasaki
Kunio Kasugai

Background: The symptom improvement rate is low with proton pump inhibitors (PPIs) in nonerosive reflux disease (NERD). The underlying pathogenic mechanism is com

Keywords:

Nerd
Refractory
Disease
Gastroenterology
Esophageal motor disorder
Reflux
Diabetes mellitus
Medicine
Internal medicine
Esophageal motility disorder
Proton-pump inhibitor
symptom onset

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