EVALUATION OF TG/HDL CHOLESTEROL RATIO AND NON HDL/HDL RATIO AS A MARKER OF CARDIOVASCULAR RISK IN DIABETICS MELLITUS

Aim: The aim of our study was to determine lipid prole levels in diabetics and nondiabetics and to evaluate cardiovascular risk using TG/HDLc ratio and Non HDLc/HDLc ratios. Study Design: A hospital based cross sectional study was conducted on patients attending the Out Patient Department of Medicine of Doon Medical College, Dehradun (Uttarakhand) during a period of 06 months from January 2018 to June 2018. 200 patients (100 Diabetics + 100 Nondiabetics) in the age group 30-80 years were selected randomly for the study. Of the 100 Diabetics (52 Male + 48 Female) and of the 100 Non diabetics 56 were males and 44 were females. All the participants underwent biochemical analysis-FBS, PPBS, HbA1C and lipid prole (TC, TG, HDL), LDL, VLDL and Non-HDL were calculated by computational methods. TG/HDLc ratio and Non HDLc/HDLc ratios were also calculated to assess cardiovascular risk. Methodology: Biochemical & statistical analysis was done on all the selected 200 subjects. TG/HDL ratio and Non-HDLc/HDLc ratios were calculated. Results: Total Cholesterol, TG, LDL & TG/HDLc ratio & Non-HDL/HDL ratio were found to be signicantly increased in diabetics when compared with non diabetics. HDL levels were found to be & slightly less in diabetics as compared to Non diabetics. Conclusion: We concluded that Non HDlc/HDLc ratio & TG/HDLc ratio can be used as early markers of cardiovascular risk.