Synthesis of Bis(indolyl)methanes through an Alkylation Reaction of Indoles with Sodium Alkoxides
2021
Herein we wish to describe an alkylation reaction of indoles with sodium alkoxides for the synthesis of bis(indolyl)methanes. 1-Tetralone was proved to be an efficient hydrogen acceptor thus avoiding the use of precious transition metals such as Ru and Ir. This reaction features transition metal-free conditions, readily available starting materials, and gram-scale synthesis.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
12
References
0
Citations
NaN
KQI