Desflurane Does Not Produce Hepatic or Renal Injury in Human Volunteers

We examined the potential toxicity of desflurane in 13 young 25.0 ± 2.3 (mean ± SD) yr-old men, given 7.35 ± 0.81 MAC-hours of desflurane anesthesia. Hepatic and renal function tests, serum electrolytes, and standard urine and hematologic tests were performed before, during, and after anesthesia. No