The effect of tamarindus indica extracts on larval stage of Echinococcus granulosus parasite in vivo and in vitro study

It is known that medicinal plants are the most important alternative to chemical drug resources, especially for antimicrobial and parasite targets and the treatment of various diseases. The present study aimed at determining the effect of aqueous and alcohol extracts of the leaves of the Tamarindus indica plant on the vitality of the protoscolices of sheep in vitro. The results study show that alcohol and aqueous extract solutions used had an inhibitory effect on protoscolices compared with control group over all concentration range. The percentage of homicide was measured by using the eosin stain test, which depends on changing the green color of the alive protoscolices to red after killing it. The study revealed that the concentration of 100 mg / ml was the optimal focus for killing the protoscolices after 4 hours of exposure. It was observed that when laboratory animals were injected with the protoscolices treated with the extracts, the protoscolices failed in the formation of secondary hydatid cysts.