Total Synthesis of rac-Silyhermin and Its 2-Diastereomers of Potential Antihepatotoxic Activity.

Sándor Antus,Eszter Baitz-Gács,Agnes Gottsegen,Otto Seligmann,Hildebert Wagner

Total Synthesis of rac-Silyhermin and Its 2-Diastereomers of Potential Antihepatotoxic Activity.

1993

Sándor Antus
Eszter Baitz-Gács
Agnes Gottsegen
Otto Seligmann
Hildebert Wagner

The first synthesis of racemic silyhermin (rac-1a) and its 2-diastereomers 1b (as a ca. 1:1 mixture) was accomplished by starting from caffeic acid ethyl ester and coniferyl alcohol.

Keywords:

Diastereomer
Total synthesis
Chemistry
Organic chemistry

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