Abstract 14700: Impact of Hemodialysis on Left Ventricular Systolic and Diastolic Properties Before and After Dialysis: a Three-dimensional Speckle Tracking Echocardiography Study

Introduction: Most patients with dialysis have left ventricular (LV) hypertrophy and fibrosis which may result in heart failure. Although estimation of LV function and fluid status is helpful in treatment of dialysis patients, noninvasive evaluation of LV function has not been fully performed. Hypothesis: We sought to evaluate LV systolic and diastolic properties in dialysis patients by 3-dimensional speckle tracking echocardiography (3D-STE) just before and after dialysis. Methods: Left atrial and LV function were measured in 64 patients with dialysis (age; 63±13, 27 men) and 40 controls (age; 65±7, 20 men) by 3D-STE. Pulmonary capillary wedge pressure (ePCWP) was estimated as 10.8 - 12.4 x log (LA active emptying function / min. LAV). Isovolumic relaxation (IVR) time was obtained by Doppler echo. Time constant of LV pressure decline (Tau) as index of relaxation was estimated as IVR time / (ln 0.9 x systolic blood pressure - ln ePCWP). LV stiffness was estimated by diastolic stress / strain. LV stress wa...