Synthèse d'hétérocycles à 5 et 6 chaînons par une stratégie combinant des réactions SNAr et SRN1

Synthesis of 5- and 6-membered heterocycles by a strategy combining S N Ar and S RN 1 reactions. The S RN 1 mechanism is compatible with many substituents on the benzenic substrate and allows S RN 1 reactions to be combined with S N Ar reactions in a strategy which brings together their corresponding synthetic advantages. Thus, compounds containing benzene fused to 5- or 6-membered heterocycles containing N (indoles), N and P (benzazaphospholes) and N and S (benzothiazines) are readily obtained.