Radioguided Surgery in Oncological Surgery

The concept of radioguided surgery involves the use of a radiation detection probe system for the intraoperative detection of radionuclides. The use of gamma detection probe technology in radioguided surgery has expanded tremendously and has evolved into what is now considered an established discipline within the practice of surgery, revolutionizing the surgical management of many malignancies, including breast cancer, melanoma and colorectal cancer. The specific application of monoclonal antibodies to radioguided surgery has been the basis for the development of radioimmunoguided surgery; the use of oncotrophic or lymphotrophic tracers is the basic principle of radioguided surgery.