Three-Dimensional Cell Culture Assays: Are They More Predictive of In Vivo Efficacy than 2D Monolayer Cell-Based Assays?

Sitta Sittampalam: Welcome to this roundtable discussion. I am a senior scientist and senior advisor to the director of the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH). Previously, I was a faculty member at the University of Kansas Medical Center for 4 years, where I was doing research on circulating tumor cells and their relation to cancer stem cells.