OP-83 Demographics, Clinical Characteristics and One-year Mortality Results of the Patients with Non-ST-Elevation Acute Coronary Syndromes

Age (years) 63;29 STEMI (n,%) 23,25 The Relationship between Alteration in QRS Fragmentation and in-Hospital Outcomes in Acute Myocardial Infarction Treated with Primary Percutenous Male (n,%) 73,45 Hypertension (n,%) 45,67 Diabetes (n,%) 34,67 Smoking (n,%) 45,43 Site of culprit lesion LAD (n,%) 73,23 LCX (n,%) 13,37 RCA (n,%) 13,40 Time to resuscitation (min.) 24,23 Time to PCI (min.) 140,45 Time to hypotermia (min.) 2880 In hospital mortality (%) 56,45 Coronary Intervention. Kaan Okyay, Ali Coner, Gokhan Ozyildiz, Mustafa Yilmaz, Serhat Balcio glu, Alp Aydinalp, Aylin Yildirir, Haldun Muderriso glu. Department of Cardiology, Baskent University, Ankara, Turkey; Department of Cardiology, Baskent University, Alanya, Turkey; Department of Cardiology, Baskent University, Adana, Turkey. Objectives: Fragmented QRS(fQRS), defined as additional spikes within the QRS complex, has been proven as an indicator of worse outcomes in a variety of cardiovascular disorders. However, the importance of alterations in fQRS in the course of acute ST elevationmyocardial infarction (STEMI) still needs to be evaluated in further studies. In this study, we sought to investigate the relationship between fragmentation processes and in-hospital outcomes in STEMI patients treated with primary PCI. Methods: 224 consecutive STEMI patients who underwent primary PCI were enrolled in our study. The cardiac outcomes during hospitalization period were defined as cardiac death, reinfarction, development of congestive heart failure, cerebrovascular events and life threatening arrhythmias. fQRS was screened at admission, during hospitalization and before hospital discharge. Results: First, patients were categorized into two groups according to apparence of any fQRS during follow-up period. fQRS group (n1⁄499) had higher incidence of cardiac outcomes (22.7% vs 8.8%, p1⁄40.014) and lower left ventricular ejection fraction (40.8 7.9 % vs 43.1 6.9, p1⁄40.028) compared to non-fQRS group (n1⁄4125). Then, patients were divided into four subgroups. Group 1; patients with fQRS at hospital admission but disapparence at hospital discharge (n1⁄423), group 2; patients with fQRS both at admission and at hospital discharge (n1⁄435), group 3; patientswith no fQRS at admission but seen at hospital discharge (n1⁄441) and group 4; patients with no fQRS either at admission or at hospital discharge (n1⁄4125). The incidences of cardiac outcomes were as following (26.1%, 22.9%, 22.0% and 8.8%, p1⁄40.027). Conclusion: In STEMI patients underwent successful primary PCI, fragmented QRS was related to worse outcomes either seen at admission or detected during hospitalization period. The best prognosis was shown in lack of any fQRS in the setting of STEMI.