FOXO3A DEFICIENCY PROTECTS FROM COXSACKIEVIRUS B3 MYOCARDITIS: ROLE OF NK CELL FUNCTION

Coxsackievirus B3 (CVB3) myocarditis can lead to dilative cardiomyopathy and heart failure. Cardiac injury is mediated by direct viral damage and host immune response. FOXO transcription factors play key roles in immunoregulation and stress resistance, including anti-inflammatory effects. We