Structural and functional changes in the parathyroid glands in patients with periodic disease

: The results obtained during radioimmunoassay, biochemistry and morphological studies in patients with periodic disease point to the development of hypoparathyroid hormonemia, reduction of the substrate of the parathyroid parenchyma, responsible for the synthesis of parathyroid hormone. These alterations became aggravated in the course of the development of amyloidosis. The latter is not always related to amyloidosis of the parathyroid glands themselves.