Ester derivative of high veratryl alcohol and medical treatment application

The invention discloses an ester derivative of high veratryl alcohol and medical treatment application, and belongs to the field of medicines. A compound with biological activity is a compound in a general formula (I) shown in the specification, and salt, a solvate or a hydrate of the compound, wherein X1 is H or COR1, X2 is H or COR2, X3 is H or COR3, but X1, X2 and X3 are not H and 3-pyridyl simultaneously; R1, R2 and R3 are the same as one another or different from one another and are C1-C6 alkyl substituted by R4 or can be substituted by R9 at random and can contain one or more 4-7-membered rings of additional heteroatom of O, S(O)n and NR9; R4 is F, CF3, OR5, NR6R7 or S(O)nR8; R5, R6 and R7 are the same as one another or different from one another and are H or C1-C6 alkyl substituted by R4 at random, or NR6R7 is one or more C4-C6 heterocycle alkyl rings of the heteroatom of O, NR9 and S(O)n; each n is 0 to 2; R8 is C1-C6 alkyl; R9 is C1-C4 alkyl which is defined by R4 or substituted by R4 or halogens at random; and R9 is H or C1-C6 alkyl. The ester derivative has the effect of treating liver diseases, T-cell proliferation related diseases or proinflammatory cytokine mediated diseases.